Cain set for second start since return from DL

In the time that Jenrry Mejia has been away from the Mets, Jeurys Familia has established himself as the team's unquestioned closer, so successful in that role that he is a Final Vote candidate for the National League All-Star team. But Mejia's return still looms significant in Tuesday's game against the Giants at AT&T Park, which pits veteran right-handers Bartolo Colon and Matt Cain against one another.