BOSTON — When the Giants arrived at Fenway Park on Friday, Tony Vitello did some pregame work in a black t-shirt that read “Whose Car We Gonna Take?” Later, that clip from “The Town” was mixed into the hitters’ meeting, along with others from movies filmed in Boston.

A young team was happy to spend three days in Boston and at a historic ballpark, but the trip ended up being a nightmare.

The Giants lost 5-4 on Sunday, completing a sweep by the Red Sox. They also lost two more players to injuries at a time when they’re already very short on healthy position players on the 40-man roster.

The Giants now are 52-78, matching their record through 130 games in 2017, when they lost 98 times. They need to win 11 of their final 32 games to avoid their second ever 100-loss season. Second Time OutMatt Wilkinson was an opener in his big-league debut, but Vitello planned to let him go as long as he was effective on Sunday. That ended up being around three innings.

Wilkinson’s velocity and command dropped off in the fourth and he was replaced after a bad break with two outs. Connor Wong hit a high...