Hunter Pence hit his career-best 26th home run to back a shaky outing by Ryan Vogelsong and the San Francisco Giants beat the San Diego Padres 7-3 Friday night.San Diego Padres' Jesus Guzman walks to the dugout after striking out against San Francisco Giants pitcher Santiago Casilla during the eighth inning of a baseball game in San Francisco, Friday, Sept. 27, 2013.San Francisco Giants pitcher Ryan Vogelsong throws against the San Diego Padres during the first inning of a baseball game in San Francisco, Friday, Sept. 27, 2013.San Francisco Giants' Juan Perez, right, celebrates with Pablo Sandoval (48) after hitting a two-run home run off of San Diego Padres pitcher Burch Smith to score Sandoval during the second inning of a baseball game in San Francisco, Friday, Sept. 27, 2013.San Diego Padres catcher Nick Hundley, left, tags out San Francisco Giants' Gregor Blanco trying to score after hitting a triple that scored Juan Perez during the eighth inning of a baseball game in San Francisco, Friday, Sept. 27, 2013. Also pictured is home plate umpire Rob Drake.