Denard Span homered and drove in five runs in his San Francisco debut, and the Giants beat the Milwaukee Brewers 12-3 in an opener Monday despite a sluggish start from under-the-weather ace Madison Bumgarner. Span hit a three-run shot with two outs in the eighth inning and Joe Panik and Buster Posey followed with home runs off Ariel Pena. It marked the first time the Giants had connected for three straight homers on opening day.