The San Diego Padres are a juggernaut — one of two in the National League West this season, alongside the Dodgers — and the Giants going to Southern California and winning a three-game series against their upstart rivals would go a long way to restoring some of that lost optimism. Yes, do that, and Giants fans might be thinking that this year might, indeed, be different. A strong start from newcomer Anthony DeSclafani on Monday night could set that tone.