Wilmer Flores hit his third homer of the season and drove in four runs to lead the San Francisco Giants over the Houston Astros 7-2 on Monday night. Giants starter Jordan Hicks (1-0), who grew up in suburban Houston, allowed only a first-inning single and struck out six in six innings. There were two on with two outs in the sixth when Flores sent a slider from Luis Contreras into the left-field seats to make it 5-0.